We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
Read More
9
Deprox 500® shows symptom improvement
Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments.
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
Read More
Most Useful Reviews
9
Cycle regularity
1 people found this helpful
Following my doctor's recommendation, I take this folate regularly and have experienced pleasing results: my cycle is now regular, and my pelvic pain has disappeared.
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9
Menstrual pain relief
Very small, convenient capsules that helped alleviate my pelvic pain during menstruation.
Read More
9
Cramp improvement
I didn’t notice obvious changes while taking this, but my pelvic cramps remarkably improved, changing from excruciating pain to manageable discomfort.
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
Read More
9
Deprox 500® shows symptom improvement
Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments.
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.4
All Reviews
Positive Reviews
Negative Reviews
9
Cycle regularity
1 people found this helpful
Following my doctor's recommendation, I take this folate regularly and have experienced pleasing results: my cycle is now regular, and my pelvic pain has disappeared.
Read More
9
Menstrual pain relief
Very small, convenient capsules that helped alleviate my pelvic pain during menstruation.
Read More
9
Cramp improvement
I didn’t notice obvious changes while taking this, but my pelvic cramps remarkably improved, changing from excruciating pain to manageable discomfort.
Read More
6
Pain reduction
5 people found this helpful
I'm planning for a pregnancy. After a month, my pelvic pain decreased, and my periods became regular and lighter. My complexion improved too. As my doctor advised, I take it twice a day alongside methyl folate, Vitamin D, and omega 3. Perhaps this combination has positively affected my body. I hope it helps my preparations for pregnancy.
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9
No stomach issues
3 people found this helpful
This product has a natural folic acid formulation and does not cause any stomach pain, which I've appreciated.
Pelvic pain is a broad term that describes discomfort occurring in the lower abdomen or pelvic region. It can stem from various underlying conditions, involving reproductive organs, the urinary tract, or gastrointestinal issues. Common causes include menstrual cramps, endometriosis, pelvic inflammatory disease, ovarian cysts, and urinary tract infections. Additionally, pelvic pain can be acute, occurring suddenly and sharply, or chronic, lasting for six months or more, significantly impacting one’s quality of life.
Managing pelvic pain often begins with a thorough evaluation from a healthcare provider to determine the underlying causes. Treatment options can vary widely based on the diagnosis and may include medication for pain relief, physical therapy, lifestyle changes, or, in some cases, surgery. Lifestyle adjustments, such as heat therapy and relaxation techniques, can also provide relief. Given the diverse nature of pelvic pain, it’s essential for individuals experiencing persistent discomfort to consult a medical professional for an accurate diagnosis and personalized treatment plan.
Folic acid, also known as vitamin B9, is a water-soluble vitamin that plays a crucial role in many bodily functions, particularly in the synthesis of DNA and RNA. It is essential for cell division and is especially important during periods of rapid growth, such as during pregnancy and infancy. The body cannot produce folic acid on its own, which is why it must be obtained from dietary sources or supplements. Commonly found in leafy green vegetables, legumes, seeds, and fortified foods, folic acid is vital for preventing neural tube defects in developing fetuses and is often recommended for women of childbearing age.
In addition to its key role in pregnancy, folic acid contributes to the production of red blood cells and can help reduce the risk of certain types of anemia. Research has also suggested that adequate folic acid levels may be associated with lowered risk of heart disease and other health issues. Most health organizations recommend a daily intake of 400 micrograms for adults, with higher amounts suggested for pregnant women. Incorporating folate-rich foods into your diet, or considering supplementation, can help ensure you meet your folic acid needs.
Folic acid, a B vitamin essential for many bodily functions, is primarily known for its role in preventing neural tube defects during pregnancy and supporting overall cellular health. While it is crucial for metabolic processes, its direct role in alleviating pelvic pain is not well established in current medical literature. Pelvic pain can arise from various underlying conditions, including endometriosis, pelvic inflammatory disease, and muscular issues, among others. Therefore, focusing on a well-rounded approach to pelvic pain management is essential, which may include dietary adjustments, physical therapy, and medical treatments specific to the underlying cause of the pain.
That said, some individuals report that a balanced diet rich in vitamins and minerals, including folic acid, can contribute to overall well-being, potentially making them feel better in a general sense. However, it is important to note that while maintaining adequate folic acid levels is beneficial for health, it should not be viewed as a primary treatment for pelvic pain. It is essential to consult a healthcare professional for a proper diagnosis and tailored treatment options that address the specific cause of the pain.
Users generally report varying timelines for witnessing the effects of the supplement on pelvic pain. Some individuals, like the reviewer who noted significant relief of pelvic pain after more than two weeks of consistent use Read Review, suggest that initial improvements can be experienced within just a couple of weeks. Others claim more immediate effects, such as the user who stated that their pelvic pain during PMS vanished almost immediately upon starting the supplement Read Review.
However, a recurring theme in user experiences is that a full month of consistent use may be needed to see substantial results. For instance, one reviewer mentioned a noticeable decrease in pelvic pain after a month, along with improvements in menstrual regularity and flow Read Review. Overall, while some users feel changes relatively quickly, a period of four weeks appears to be a common timeframe for many to realize significant improvement in their symptoms.
This supplement shows promising support in scientific research for alleviating pelvic pain. A clinical trial investigated the efficacy of a product called Deprox 500®, which contains flower pollen extract with vitamins, and found that participants with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) experienced significant symptom improvements compared to those taking a placebo. Notably, patients with hypertension benefited even more, indicating that this treatment may enhance quality of life in individuals suffering from pelvic pain [2].
Another study focused on an innovative treatment using folic acid-modified nanoparticles designed to target chronic bacterial prostatitis (CBP). In animal models, this novel approach not only reduced pelvic pain but also decreased inflammatory markers, highlighting its potential effectiveness. However, as with many promising findings, further research is required to translate these results into clinically effective treatments for humans [1]. Overall, the evidence suggests that specific supplements might serve as beneficial options for those battling pelvic pain, but it's important to consult a healthcare professional before starting any new treatment.
Users have reported a range of improvements in their symptoms after taking this methyl folate supplement. A number of reviewers noted significant decreases in pelvic pain, particularly during menstruation. For instance, one user shared that their pelvic pain vanished almost immediately after starting the supplement, attributing the relief to its formulation Read Review. Another user reported a transformation in their menstrual cramps, moving from excruciating pain to manageable discomfort, after a month of use Read Review.
Additionally, many users found improvement in their menstrual cycles, with increased regularity and lighter flow being common benefits. One reviewer stated their cycle became regular and their periods significantly lighter after using the supplement alongside other vitamins Read Review. Though these accounts are encouraging, it is important to note that individual results may vary—while some users experienced rapid relief, others found their improvements more gradual or did not notice any benefits at all Read Review. Overall, the experiences shared in these reviews suggest that many individuals have found positive outcomes, particularly concerning pelvic pain and menstrual health.
Users have reported positive outcomes when combining this methyl folate supplement with other vitamins to manage pelvic pain. For instance, one reviewer noted that taking the supplement alongside methyl folate, Vitamin D, and Omega 3 led to a significant decrease in pelvic pain and lighter menstrual periods after consistent use Read Review. Another user highlighted a similar experience, emphasizing that following their doctor's advice to take multiple supplements resulted in improvements not only in pelvic pain but also in menstrual regularity and ease during periods Read Review.
Additionally, other users have noted the benefits of pairing the methyl folate with evening primrose oil, which they found helpful in alleviating pelvic pain Read Review. However, it is essential to acknowledge that not everyone experienced similar results, with some users reporting adverse reactions or lack of improvement after combining the supplement with other substances Read ReviewRead Review. Overall, while many users have reported favorable experiences with combinations of supplements for managing pelvic pain, individual responses can vary widely.
Based on user reviews, there is a range of experiences regarding the optimal dose of Folic Acid (or its active form, methylfolate) for alleviating pelvic pain. Many users report positive outcomes when following their doctor's recommendations, with some taking it twice daily, particularly in combination with other supplements like Vitamin D and omega-3, which they believe enhances the benefits. For instance, one user noted a marked reduction in pelvic pain after taking it as directed for a month alongside advice from her doctor Read Review. Others have experienced similar improvements with compliant dosages Read Review.
However, not every user reports effective results; some mention lingering or worsening symptoms after taking folic acid, or they simply find it ineffective for their specific issues Read Review. Overall, while many advocate for a twice-daily regimen as beneficial, it appears that individual responses can vary widely, making it critical for those considering folic acid for pelvic pain to consult with healthcare providers to determine the right personal dosage based on their unique needs and medical history.
7.5
Continued use
1 people found this helpful
After taking this for more than two weeks, I noticed the absence of pelvic pain and unpleasant sensations. There was an unusual delay in my cycle, which typically does not occur. I will continue taking this product.
8
Skin improvement
1 people found this helpful
I was initially worried about skin issues and pelvic pain related to my multifollicular ovaries. My gynaecologist prescribed inositol and folate. I found this methylfolate from Jarrow formulas, noting immediate effects: my pelvic pain during PMS vanished, and my skin cleared significantly, reducing pesky closed comedones.
6
Pain reduction
5 people found this helpful
I'm planning for a pregnancy. After a month, my pelvic pain decreased, and my periods became regular and lighter. My complexion improved too. As my doctor advised, I take it twice a day alongside methyl folate, Vitamin D, and omega 3. Perhaps this combination has positively affected my body. I hope it helps my preparations for pregnancy.
9
Cramp improvement
I didn’t notice obvious changes while taking this, but my pelvic cramps remarkably improved, changing from excruciating pain to manageable discomfort.
0
Not effective
1 people found this helpful
To be honest, I didn't like these folates. After taking them, I experienced lower abdominal pain. Perhaps it's a coincidence, but the pain disappeared once I stopped taking the pills.
7.5
Reduced symptoms
1 people found this helpful
After a month of use, my pelvic pain during PMS decreased, and my period became lighter. I take it twice daily, as the doctor advised, alongside methyl folate, Vitamin D, and Omega 3. This combination seems beneficial in preparing for my planned pregnancy.
7.5
Effective remedy
1 people found this helpful
I took this supplement to maintain my women's health, following my doctor's advice. Although I'm not planning a pregnancy yet, I will buy this product when I do. It worked well with evening primrose oil: my pelvic pain during my period decreased, and overall, it seems beneficial for my cardiovascular health.
0
Severe side effects
Despite the title, my experience was more about my individual intolerance than the drug itself. I suffered abdominal pains, diarrhoea, and severe nausea, while another drug only caused nausea and dizziness. Doctors insist I try again, but I'm hesitant due to the unbearable experience. Interestingly, my friends enjoy this particular folic acid. I'm curious if others have experienced similar side effects.
9
Deprox 500® shows symptom improvement
Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments.
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
9
Folic acid nanomedicine alleviates pain
Antibiotic-loaded reactive oxygen species-responsive nanomedicine for effective management of chronic bacterial prostatitis.
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
References
Zheng J, Hu R, Yang Y, Wang Y, Wang Q, et al. Antibiotic-loaded reactive oxygen species-responsive nanomedicine for effective management of chronic bacterial prostatitis. Acta Biomater. 2022;143:471. doi:10.1016/j.actbio.2022.02.044
Macchione N, Bernardini P, Piacentini I, Mangiarotti B, Del Nero A. Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments. Antiinflamm Antiallergy Agents Med Chem. 2019;18:151. doi:10.2174/1871523018666181128164252